Just to clarify, this is not an advisory page (or website!).
We are a distributor. We are not big pharma, scientists, healthcare professionals or drug manufacturers.
We try out best bring to market the purest chemicals for laboratory research, and the stuff we bring in has been classified as 'SARMs'. We ensure quality from raw material, to packaging, to your door. If we play by the rules, we can continue to do this for years to come.
There are many sources available for the information you are seeking but we are neither qualified nor allowed legally to advise on your research study.
We have however, broken down research links and given an overview of the role of SARMs.
Each SARM in production has specific functions it performs well, so SARM research protocols should be tailored for specific goals and uses.
What we can tell you..
Sales trend analysis we have done suggests most researchers choose one primary compound, such as RAD-140 or LGD-4033 or S-23 or S-4. More is not always better.
If and when a study involves multiple goals we generally see a primary compound purchased with one or more secondary compounds (such as, MK-2866, or GW-501516 and/or SR-9009, or YK-11, or MK-677
Today there are many SARMs in various stages of testing, where there are many positive findings, however, there is also research that has establised less than positive findings, side-effects or lack of biological efficiency or scientific efficacy.
REMEMBER
When researching the SARMs for your specific use case, keep in mind that these chemicals have yet to be approved for human consumption. While current research and growing anecdotal evidence indicates SARMs could be promising, more research is needed to understand the long-term effects of these compounds.
MK-2866
Ostarine is a type of drug called a selective androgen receptor modulator (SARM). It's not approved by the FDA, but is sometimes found in supplements.
Ostarine attaches to proteins in the body known as androgen receptors. When ostarine binds to these receptors, it tells muscles to grow.
People use ostarine for athletic performance, involuntary weight loss due to illness,breast cancer, and many other conditions, but there is no good scientific evidence to support these uses.
Ostarine is an investigational drug and therefore not approved for any use by the US FDA. Despite this, it is still sometimes found in dietary supplements, particularly those marketed for bodybuilding. Ostarine, along with other SARMS, is banned by the World Anti-Doping Agency (WADA) and the National Collegiate Athletic Association (NCAA).
Extract above taken from: https://www.webmd.com/vitamins/ai/ingredientmono-1564/ostarine
More information from public sources can be found here:
Please note, we take no responsilitiy for any references that may now be outdated.
MK-2866 (Ostarine) Chemical Profile:
https://en.wikipedia.org/wiki/Enobosarm
RAD-140
RAD140 is an investigational selective androgen receptor modulator (SARM) that is developed by Radius Health, Inc. for use in androgen replacement therapy. It was licensed to Ellipses Pharmaceuticals in 2020.[1][2][3][4]Some of the potential benefits under investigation are for the treatment of conditions such as muscle wasting and bone loss.
Extract above taken from:
https://en.wikipedia.org/wiki/RAD140
More information from public sources can be found here:
https://en.wikipedia.org/wiki/RAD140#References
https://www.webmd.com/vitamins/ai/ingredientmono-1651/testolone-%5Bfast-facts%5D
Please note, we take no responsilitiy for any references that may now be outdated.
RAD-140 (Testalone) Chemical Profile:
LGD-4033
Ligandrol (VK5211, LGD-4033)[2] is a novel nonsteroidal oral selective androgen receptor modulator (SARM) for treatment of conditions such as muscle wasting and osteoporosis,[3] discovered by Ligand Pharmaceuticals and under development by Viking Therapeutics.[4][5]
Ligandrol has been found in World Anti-Doping Agency (WADA) samples and in racehorses too. Like anabolic steroids, it can stimulate muscle growth. "SARMs have shown superior side effect profiles compared with anabolic steroids, which arguably makes them attractive for use by individuals seeking an unfair advantage over their competitors".[6]
Extract above taken from:
https://en.wikipedia.org/wiki/Ligandrol
More information from public sources can be found here:
https://en.wikipedia.org/wiki/Ligandrol#References
https://www.webmd.com/vitamins/ai/ingredientmono-1650/ligandrol-%5Bfast-facts%5D
Please note, we take no responsilitiy for any references that may now be outdated.
LGD-4033 Chemical Profile can be found here:
https://en.wikipedia.org/wiki/Ligandrol
SR-9009
SR9009, also known as Stenabolic, is a research drug that was developed by professor Thomas Burris of the Scripps Research Institute as an agonist of Rev-ErbA (i.e., increases the constitutive repression of genes regulated by Rev-ErbA)[1] with a half-maximum inhibitory concentration (IC50) = 670 nM for Rev-ErbAα and IC50 = 800 nM for Rev-ErbAβ.[2]
Activation of Rev-ErbA-α by SR9009 in mice increases exercise capacity by increasing mitochondria counts in skeletal muscle.[3]
Abuse of SR9009 has been reported within the bodybuilding community, resulting in SR9009 being placed on the World Anti-Doping Agency list of prohibited drugs. SR9009 and the related SR9011 drug are described as "Hormone and Metabolic Modulators".[4][5]
Extract above taken from:
https://en.wikipedia.org/wiki/SR9009
More information from public sources can be found here:
https://en.wikipedia.org/wiki/SR9009
https://www.webmd.com/vitamins/ai/ingredientmono-1649/stenabolic-%5Bfast-facts%5D
Please note, we take no responsilitiy for any references that may now be outdated.
SR-9009 (Stenabolic) Chemical Profile:
GW-501516
GW501516 (also known as GW-501,516, GW1516, GSK-516, Cardarine, and on the black market as Endurobol[1]) is a PPARδ receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s. It entered into clinical development as a drug candidate for metabolic and cardiovascular diseases, but was abandoned in 2007 because animal testing showed that the drug caused cancer to develop rapidly in several organs.[2]
In 2007, research was published showing that high doses of GW501516 given to mice dramatically improved their physical performance; the work was widely discussed in popular media, and led to a black market for the drug candidate and to its abuse by athletes as a doping agent. The World Anti-Doping Agency (WADA) developed a test for GW501516 and other related chemicals and added them to the prohibited list in 2009; it has issued additional warnings to athletes that GW501516 is not safe.
Extract above taken from:
https://en.wikipedia.org/wiki/GW501516
More information from public sources can be found here:
https://en.wikipedia.org/wiki/GW501516#References
https://www.webmd.com/vitamins/ai/ingredientmono-1648/cardarine-%5Bfast-facts%5D
Please note, we take no responsilitiy for any references that may now be outdated.
GW-501516 Chemical Profile:
MK-677
Ibutamoren (INN) (developmental code names MK-677, MK-0677, L-163,191; former tentative brand name Oratrope) is a potent, long-acting, orally-active, selective, and non-peptide agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin.[3][4][5][6][7] It has been shown to increase the secretion of several hormones including GH and insulin-like growth factor 1 (IGF-1) and produces sustained increases in the plasma levels of these hormones without affecting cortisol levels.[8]
Ibutamoren has been shown to sustain activation of the GH–IGF-1 axis and to increase lean body mass with no change in total fat mass or visceral fat. It is under investigation as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with growth hormone deficiency,[3][9][10][11] and human studies have shown it to increase both muscle mass and bone mineral density,[12][13] making it a promising potential therapy for the treatment of frailty in the elderly.[14][15] As of June 2017, ibutamoren is in the preclinical stage of development for growth hormone deficiency.[3]
Since MK-677 is still an Investigational New Drug, it has not yet been approved to be marketed for consumption by humans in the United States.[3] However, it has been used experimentally by some in the bodybuilding community. Since it chemically mimics the hormone ghrelin, it functions as a neuropeptide in the central nervous system and crosses the blood-brain-barrier.[4][5][6][7] According to some recent research and discussion, there is a concern that its particularly longer half-life might over-stimulate the ghrelin receptors in the brain.[16]
Extract above taken from:
https://en.wikipedia.org/wiki/Ibutamoren
More information from public sources can be found here:
https://en.wikipedia.org/wiki/Ibutamoren
Please note, we take no responsilitiy for any references that may now be outdated.
MK-677 (Ibutamoren) Chemical Profile:
S-4
Andarine (developmental code names GTx-007, S-4) is an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy,[1] using the nonsteroidal antiandrogen bicalutamide as a lead compound.[2]
Andarine is an orally active partial agonist of the androgen receptor (AR). In intact male rats, 0.5 mg andarine daily was shown to reduce prostate weight to 79.4%, and non-significantly increased levator ani muscle weight. In castrated male rats, this dose restored only 32.5% prostate weight, but 101% levator ani muscle weight [3] This suggests that andarine is able to competitively block binding of dihydrotestosterone to its receptor targets in the prostate gland, but its partial agonist actions at the androgen receptor prevent the side effects associated with the antiandrogens traditionally used for treatment of BPH.[4]
Extract above taken from:
https://en.wikipedia.org/wiki/Andarine
More information from public sources can be found here:
https://en.wikipedia.org/wiki/Andarine
https://www.webmd.com/vitamins/ai/ingredientmono-1649/stenabolic-%5Bfast-facts%5D
Please note, we take no responsilitiy for any references that may now be outdated.
S4 Chemical Profile:
S-23
S-23 is an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc as a potential male hormonal contraceptive. It binds to the androgen receptor more strongly than older drugs such asandarine with aKi of 1.7 nM, and in animal studies it showed both a good ratio of anabolic to androgenic effects, and dose-dependent suppression of spermatogenesis with spontaneous recovery after cessation of treatment.[1][2]
Extract above taken from:
https://en.wikipedia.org/wiki/S-23_(drug)
More information from public sources can be found here:
https://en.wikipedia.org/wiki/S-23_(drug)
https://www.webmd.com/vitamins/ai/ingredientmono-1652/s-23-%5Bfast-facts%5D
Please note, we take no responsilitiy for any references that may now be outdated.
S23 Chemical Profile:
YK-11
YK-11 is reported to be a synthetic steroidal selective androgen receptor modulator[1][2] It is a gene-selective partial agonist of the androgen receptor (AR) and does not induce the physical interaction between the NTD/AF1 and LBD/AF2 (known as the N/C interaction), which is required for full transactivation of the AR.[1][2] The drug has anabolic activity in vitro in C2C12 myoblasts and shows greater potency than dihydrotestosterone(DHT) in this regard.[2]It has been investigated as a potential treatment forsepsis-induced muscle wasting in animal studies.[3]
YK11 is a steroid made by altering the chemical structure of DHT. In contrast, all other SARMs have a nonsteroidal structure. YK11 and SARMs work differently in the body and may have different side effects [2, 6].
Cell studies do show that YK11 has a selective effect on androgen receptors. This means the SARM label does technically describe YK11 [2].
Because this class of drugs is new, no established naming convention exists.
Extracts above taken from:
https://en.wikipedia.org/wiki/YK-11
https://drugs.selfdecode.com/blog/yk11/
More information from public sources can be found here:
https://en.wikipedia.org/wiki/YK-11
https://drugs.selfdecode.com/blog/yk11/
Please note, we take no responsilitiy for any references that may now be outdated.
YK11 Chemical Profile:
Flexible payment options include credit card and cryptocurrencies!
There is a reason why customers stay loyal to us, because we deliver!
We offer Advanced Shipping on worldwide orders and ship the same or next day!
